The weatherbased appraisal model of low temperature, rain/snow, and freezes disaster influence in the Southeast Guizhou is built and the damage degrees of 206 villages (towns) in Southeast Guizhou are calculated by using the weighted average method and the related meteorological factors of 16 weather stations in Southeast Guizhou during the disaster period. The results show that the low temperature, rain/snow, and freezing disaster caused great damages in Southeast Guizhou with varying degrees in different areas; there are 16 villages (towns) suffered the first grade freezing, mainly in the areas with medium elevation in the eastern part; the second grade freezing occurred mainly in the eastern part, the northern mountainous area and the western border areas; the freezing degree was relatively low over the lowlying river valley areas. Through the analysis, it is found out that the influence of the freezing disaster is related to not only the abnormal atmospheric circulation situation, but also the special terrain of Southeast Guizhou.