On the basis of meteorological data from 1965 to 2001 around the Hunshandake sandy land, the characteristics of main climatic factors and their temporal and spatial variation regularities are analyzed. The research results indicate: there are obvious differences in main climatic factors along longitudes and less obvious along latitudes in the Hunshandake sandy land; from 1965 to 2001 in the most parts of the Hunshandake sandy land, the mean annual and seasonal temperatures had an evidently increasing tendency, and the mean annual wind velocity had an evidently decreasing tendency, especially in the spring; in the main part of the sandy land, the changing tendencies of annual and seasonal precipitation were not very clear, while there were slowly increasing tendencies in the annual dry/wet index, and not very clearly decreasing tendencies in annual evaporation.